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1

Imaging guidelines for children with Ewing sarcoma and osteosarcoma: A report from the Children's Oncology Group Bone Tumor Committee

James S. Meyer, Helen R. Nadel, Neyssa Marina, Richard B. Womer, Kenneth L. B. Brown, J.F. Eary, Richard Gorlick, Holcombe E. Grier, R. Lor Randall, Elizabeth R. Lawlor, Stephen L. Lessnick, Paula J.

Journal:

Pediatric Blood & Cancer

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

2

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

Sonam Dolma, Stephen L Lessnick, William C Hahn, Brent R Stockwell

Journal:

Year:

2003

Language:

english

File:

PDF, 661 KB

english, 2003

3

Identification of Target Genes in Their Native Cellular Context

Owen, Leah A., Lessnick, Stephen L.

Journal:

Year:

2006

Language:

english

File:

PDF, 434 KB

english, 2006

4

Comparison of clinical features and outcomes in patients with extraskeletal versus skeletal localized Ewing sarcoma: A report from the Children's Oncology Group

Cash, Thomas, McIlvaine, Elizabeth, Krailo, Mark D., Lessnick, Stephen L., Lawlor, Elizabeth R., Laack, Nadia, Sorger, Joel, Marina, Neyssa, Grier, Holcombe E., Granowetter, Linda, Womer, Richard B.,

Journal:

Pediatric Blood & Cancer

Year:

2016

Language:

english

File:

PDF, 463 KB

english, 2016

5

Response to “imaging guidelines for children with Ewing sarcoma and osteosarcoma: A report from the Children's Oncology Group Bone Tumor Committee”

James S. Meyer, Helen R. Nadel, Neyssa Marina, Richard B. Womer, Kenneth L.B. Brown, J.F. Eary, Richard Gorlick, Holcombe E. Grier, R. Lor Randall, Elizabeth R. Lawlor, Stephen L. Lessnick, Paula J. S

Journal:

Pediatric Blood & Cancer

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

6

Phase II study of intermediate-dose cytarabine in patients with relapsed or refractory Ewing sarcoma: A report from the Children's Oncology Group

Steven G. DuBois, Mark D. Krailo, Stephen L. Lessnick, Richard Smith, Zhengjia Chen, Neyssa Marina, Holcombe E. Grier, Kimberly Stegmaier

Journal:

Pediatric Blood & Cancer

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

7

The Potential for molecular therapeutic targets in Ewing’s sarcoma

Nancy R. McAllister, Stephen L. Lessnick

Journal:

Current Treatment Options in Oncology

Year:

2005

Language:

english

File:

PDF, 791 KB

english, 2005

8

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

Sorensen, Poul H.B., Lessnick, Stephen L., Lopez-Terrada, Dolores, Liu, Xian F., Triche, Timothy J., Denny, Christopher T.

Journal:

Nature Genetics

Year:

1994

File:

PDF, 750 KB

1994

9

Antibody detection of translocations in Ewing sarcoma

Wen Luo, Brett Milash, Brian Dalley, Richard Smith, Holly Zhou, Natalie Dutrow, Bradley R. Cairns, Stephen L. Lessnick

Journal:

EMBO Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 991 KB

english, 2012

10

Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: A report from the childhood cancer survivor study

Steven G. DuBois, Robert Goldsby, Mark Segal, Jonathan Woo, Kirsten Copren, John P. Kane, Clive R. Pullinger, Katherine K. Matthay, John Witte, Stephen L. Lessnick, Leslie L. Robison, Smita Bhatia, Lo

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 96 KB

english, 2012

11

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

Richard Smith, Leah A. Owen, Deborah J. Trem, Jenny S. Wong, Jennifer S. Whangbo, Todd R. Golub, Stephen L. Lessnick

Journal:

Year:

2006

Language:

english

File:

PDF, 861 KB

english, 2006

12

Oncogenic MITF dysregulation in clear cell sarcoma: Defining the MiT family of human cancers

Ian J. Davis, Jessica J. Kim, Fatih Ozsolak, Hans R. Widlund, Orit Rozenblatt-Rosen, Scott R. Granter, Jinyan Du, Jonathan A. Fletcher, Christopher T. Denny, Stephen L. Lessnick, W. Marston Linehan, A

Journal:

Year:

2006

Language:

english

File:

PDF, 782 KB

english, 2006

13

Expression Profiling of EWS/FLI Identifies NKX2.2 as a Critical Target Gene in Ewing's Sarcoma

Richard Smith, Leah A. Owen, Deborah J. Trem, Jenny S. Wong, Jennifer S. Whangbo, Todd R. Golub, Stephen L. Lessnick

Journal:

Year:

2007

Language:

english

File:

PDF, 41 KB

english, 2007

14

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

Stephen L Lessnick, Caroline S Dacwag, Todd R Golub

Journal:

Year:

2002

Language:

english

File:

PDF, 433 KB

english, 2002

15

Small Round Cell Sarcomas

Stephen L. Lessnick, A. Paolo Dei Tos, Poul H.B. Sorensen, Palma Dileo, Laurence H. Baker, Stefano Ferrari, Kirsten Sundby Hall

Journal:

Seminars in Oncology

Year:

2009

Language:

english

File:

PDF, 807 KB

english, 2009

16

Promiscuous partnerships in Ewing's sarcoma

Savita Sankar, Stephen L. Lessnick

Journal:

Cancer Genetics

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

17

EWS/FLI-responsive GGAA microsatellites exhibit polymorphic differences between European and African populations

Robert Beck, Michael J. Monument, W. Scott Watkins, Richard Smith, Kenneth M. Boucher, Joshua D. Schiffman, Lynn B. Jorde, R. Lor Randall, Stephen L. Lessnick

Journal:

Cancer Genetics

Year:

2012

Language:

english

File:

PDF, 790 KB

english, 2012

18

Pediatric malignancies: update on sarcomas and leukemia development in children

Benjamin S Braun, Stephen L Lessnick

Journal:

Current Opinion in Genetics & Development

Year:

2009

Language:

english

File:

PDF, 263 KB

english, 2009

19

The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

Or Gozani, Philip Karuman, David R. Jones, Dmitri Ivanov, James Cha, Alexey A. Lugovskoy, Cheryl L. Baird, Hong Zhu, Seth J. Field, Stephen L. Lessnick, Jennifer Villasenor, Bharat Mehrotra, Jian Chen

Journal:

Year:

2003

Language:

english

File:

PDF, 717 KB

english, 2003

20

Children's Oncology Group's 2013 blueprint for research: Bone tumors

Gorlick, Richard, Janeway, Katherine, Lessnick, Stephen, Randall, R. Lor, Marina, Neyssa

Journal:

Pediatric Blood & Cancer

Year:

2013

Language:

english

File:

PDF, 142 KB

english, 2013

21

A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin

Malay Haldar, Jeffrey D. Hancock, Cheryl M. Coffin, Stephen L. Lessnick, Mario R. Capecchi

Journal:

Year:

2007

Language:

english

File:

PDF, 1.92 MB

english, 2007

22

Glutathione S-Transferases in Pediatric Cancer

Luo, Wen, Kinsey, Michelle, Schiffman, Joshua D., Lessnick, Stephen L.

Journal:

Frontiers in Oncology

Year:

2011

Language:

english

File:

PDF, 456 KB

english, 2011

23

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Sankar, S, Bell, R, Stephens, B, Zhuo, R, Sharma, S, Bearss, D J, Lessnick, S L

Journal:

Year:

2013

Language:

english

File:

PDF, 3.41 MB

english, 2013

24

Molecular Pathogenesis of Ewing Sarcoma: New Therapeutic and Transcriptional Targets

Lessnick, Stephen L., Ladanyi, Marc

Journal:

Annual Review of Pathology Mechanisms of Disease

Year:

2012

Language:

english

File:

PDF, 204 KB

english, 2012

25

β-Catenin-Induced Melanoma Growth Requires the Downstream Target Microphthalmia-Associated Transcription Factor

Hans R. Widlund, Martin A. Horstmann, E. Roydon Price, Junqing Cui, Stephen L. Lessnick, Min Wu, Xi He and David E. Fisher

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 934 KB

english, 2002

26

Diphtheria Toxin and its ADP-Ribosyltransferase-Defective Homologue CRM197 Possess Deoxyribonuclease Activity

Can Bruce, Rae Lynn Baldwin, Stephen L. Lessnick and Bernadine J. Wisnieski

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 764 KB

english, 1990

27

A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature

Hancock, Jeffrey D., Lessnick, Stephen L.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.63 MB

english, 2008

28

The Molecular Basis of Sarcoma

Lessnick, Stephen L., Kovar, Heinrich, Houghton, Peter

Journal:

Year:

2011

Language:

english

File:

PDF, 68 KB

english, 2011

29

Microsatellite Instability in Sarcoma: Fact or Fiction?

Monument, Michael J., Lessnick, Stephen L., Schiffman, Joshua D., Randall, Rl. Tx.

Journal:

Year:

2012

Language:

english

File:

PDF, 855 KB

english, 2012

30

At-Risk Populations for Osteosarcoma: The Syndromes and Beyond

Calvert, George T., Randall, R. Lor, Jones, Kevin B., Cannon-Albright, Lisa, Lessnick, Stephen, Schiffman, Joshua D.

Journal:

Year:

2012

Language:

english

File:

PDF, 116 KB

english, 2012

31

Potential for Modulation of the Fas Apoptotic Pathway by Epidermal Growth Factor in Sarcomas

Joyner, David E., Jones, Kevin B., Lessnick, Stephen L., Schiffman, Joshua D., Randall, R. Lor

Journal:

Year:

2011

Language:

english

File:

PDF, 369 KB

english, 2011

32

Ewing Sarcoma 11;22 Translocation Produces a Chimeric Transcription Factor that Requires the DNA-Binding Domain Encoded by FLI1 for Transformation

William A. May, Mikhail L. Gishizky, Stephen L. Lessnick, Lynn B. Lunsford, Brian C. Lewis, Olivier Delattre, Jessica Zucman, Gilles Thomas and Christopher T. Denny

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.14 MB

english, 1993

33

Expression of EWS-ETS Fusions in NIH3T3 Cells Reveals Significant Differences to Ewing’s Sarcoma

Braunreiter, Chi L., Hancock, Jeffery D, Coffin, Cheryl, Boucher, Kenneth M, Lessnick, Stephen L.

Journal:

Year:

2006

Language:

english

File:

PDF, 1.21 MB

english, 2006

34

Microsatellites are EWS/FLI response elements: Genomic "junk" is EWS/FLI's treasure

Gangwal, Kunal, Lessnick, Stephen L.

Journal:

Year:

2008

Language:

english

File:

PDF, 683 KB

english, 2008

35

Molecular biology of sarcomas: update-the cell cycle paradigm

Randall, R Lor, Lessnick, Stephen L, Johnson, Brian, Joyner, David E

Journal:

Current Opinion in Orthopaedics

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

36

Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma

Sankar, S, Bell, R, Stephens, B, Zhuo, R, Sharma, S, Bearss, D J, Lessnick, S L

Journal:

Year:

2016

Language:

english

File:

PDF, 398 KB

english, 2016

37

EWS/FLI is a Master Regulator of Metabolic Reprogramming in Ewing Sarcoma

Tanner, Jason M, Bensard, Claire, Wei, Peng, Krah, Nathan M, Schell, John C, Gardiner, Jamie D, Schiffman, Joshua D., Lessnick, Stephen L, Rutter, Jared

Journal:

Molecular Cancer Research

Year:

2017

Language:

english

File:

PDF, 6.70 MB

english, 2017

38

Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth

Johnson, Kirsten M., Mahler, Nathan R., Saund, Ranajeet S., Theisen, Emily R., Taslim, Cenny, Callender, Nathan W., Crow, Jesse C., Miller, Kyle R., Lessnick, Stephen L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

39

Of Mice and Men: Opportunities to Use Genetically Engineered Mouse Models of Synovial Sarcoma for Preclinical Cancer Therapeutic Evaluation

Jones, Kevin B., Haldar, Malay, Schiffman, Joshua D., Cannon-Albright, Lisa, Lessnick, Stephen L., Sharma, Sunil, Capecchi, Mario R., Randall, R. Lor

Journal:

Year:

2011

Language:

english

File:

PDF, 398 KB

english, 2011

40

EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma

Owen, Leah A., Kowalewski, Ashley A., Lessnick, Stephen L., Wu, Xiaolin

Journal:

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

41

BCL11B Is Up-Regulated by EWS/FLI and Contributes to the Transformed Phenotype in Ewing Sarcoma

Wiles, Elizabeth T., Lui-Sargent, Bianca, Bell, Russell, Lessnick, Stephen L., Lee, Sean Bong

Journal:

Year:

2013

Language:

english

File:

PDF, 2.16 MB

english, 2013

42

Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

Kowalewski, Ashley A., Randall, R. Lor, Lessnick, Stephen L.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.30 MB

english, 2011

43

Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex

Kumar P, Pavan, Emechebe, Uchenna, Smith, Richard, Franklin, Sarah, Moore, Barry, Yandell, Mark, Lessnick, Stephen L, Moon, Anne M

Journal:

Year:

2014

Language:

english

File:

PDF, 5.09 MB

english, 2014

44

Microsatellites with Macro-Influence in Ewing Sarcoma

Monument, Michael J., Johnson, Kirsten M., Grossmann, Allie H., Schiffman, Joshua D., Randall, R. Lor, Lessnick, Stephen L.

Journal:

Year:

2012

Language:

english

File:

PDF, 413 KB

english, 2012

45

The Clone Wars – Revenge of the Metastatic Rogue State: The Sarcoma Paradigm

Spraker, Holly L., Price, Shawn L., Chaturvedi, Aashi, Schiffman, Joshua D., Jones, Kevin B., Lessnick, Stephen L., Beckerle, Mary, Randall, R. Lor

Journal:

Frontiers in Oncology

Year:

2012

Language:

english

File:

PDF, 263 KB

english, 2012

46

Targeting Glutathione S-transferase M4 in Ewing sarcoma

Zhuo, Rupeng, Kosak, Kenneth M., Sankar, Savita, Wiles, Elizabeth T., Sun, Ying, Zhang, Jianxing, Ayello, Janet, Prestwich, Glenn D., Shami, Paul J., Cairo, Mitchell S., Lessnick, Stephen L., Luo, Wen

Journal:

Frontiers in Pediatrics

Year:

2014

Language:

english

File:

PDF, 648 KB

english, 2014

47

Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children’s Oncology Group

Shulman, David S., Klega, Kelly, Imamovic-Tuco, Alma, Clapp, Andrea, Nag, Anwesha, Thorner, Aaron R., Van Allen, Eliezer, Ha, Gavin, Lessnick, Stephen L., Gorlick, Richard, Janeway, Katherine A., Leav

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 477 KB

english, 2018

48

Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule Dependent Manner

Harlow, Matt L, Chasse, Maggie H., Boguslawski, Elissa A, Sorensen, Katie M., Gedminas, Jenna M, Kitchen-Goosen, Susan M, Rothbart, Scott B., Taslim, Cenny, Lessnick, Stephen L, Peck, Anderson S, Mada

Journal:

Clinical Cancer Research

Year:

2019

File:

PDF, 2.76 MB

2019

49

Increased risk for other cancers in individuals with Ewing sarcoma and their relatives

Abbott, Diana, O'Brien, Schuyler, Farnham, James M., Young, Erin L., Yap, Jeffrey, Jones, Kevin, Lessnick, Stephen L., Randall, R. Lor, Schiffman, Joshua D., Cannon‐Albright, Lisa A.

Journal:

Cancer Medicine

Year:

2019

Language:

english

File:

PDF, 153 KB

english, 2019

50

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Showpnil, Iftekhar A., Miller, Kyle R., Taslim, Cenny, Pishas, Kathleen I., Lessnick, Stephen L., Theisen, Emily R.

Journal:

Journal of Visualized Experiments

Year:

2020

File:

PDF, 1.19 MB

2020

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